Author + information
- Amerjeet Singh Banninga,b,
- Vincent Gariteya,b,
- Karim Mouniemnea,b,
- Justyna Janusa,b,
- Michael kellya,b,
- Julian Gunna,b and
- Anthony Gershlicka,b
Background: For coronary bifurcation lesions, provisional T-stent is the default strategy since two-stent strategies demonstrate worse outcomes in meta-analyses. An optimal side-branch stent design may prove otherwise. We have developed a totally novel user-friendly side branch stent with a malleable end that can be modified with main branch balloon inflation to fit any angle, and appose the side-branch ostium without luminal protrusion.
Methods: Prototype design iterations were tested using Finite Element analysis in a simulated coronary bifurcation, from which selected prototype designs were laser cut from cobalt chromium and deployed in silicone bifurcation models representing 2 shapes (λ, γ) and 3 angles (45o, 60o 75o), n=18. Micro-CT of the stented bifurcations were analyzed for proof of stent suitability.
Results: All 18 stents were successfully deployed with collapse of malleable end (Fig 1A). There was no stent protrusion into the main branch lumen at any angle (Fig 1B). Mean distance of the stent strut from vessel wall in side branch was 0.07+/-0.02mm in λ45°, 0.09+/-0.02mm in λ60° and 0.09+/-0.02mm in λ75°, <5% of vessel lumen, indicating excellent apposition.
Conclusions: These results demonstrate proof-of-concept that a stent with a in-situ malleable end can conform to the side branch ostium with good apposition in various shapes and angles. The excellent apposition characteristics may translate into improved clinical outcomes for two-stent strategies in true bifurcation lesions
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Interventional Cardiology: Translation and Pre-Clinical Research
Abstract Category: 25. Interventional Cardiology: Translation and Pre-clinical Research
Presentation Number: 1116-186
- 2017 American College of Cardiology Foundation