Author + information
- Linghong Shena,b,
- Richard Schlofmitza,b,
- Mitsuaki Matsumuraa,b,
- Jane Jie Caoa,b and
- Akiko Maeharaa,b
Background: Coronary artery calcification can be detected by both non-invasive and invasive imaging modalities. In the present study, we compared the coronary calcium detection between multi-detector computed tomography (MDCT) and optical coherence tomography (OCT).
Methods: Consecutive 47 coronary vessel segments from 43 pts with both OCT and MDCT within 3 months were evaluated retrospectively. The OCT quantitative analysis included calcium angle, maximal calcium thickness, total calcium length, which were further subcategorized based on calcium thickness (≤0.5mm, 0.5–1.0mm, ≥1.0mm). Calcium Volume Index (=mean calcium angle × calcium length) were calculated. The amount of coronary calcification by MDCT was assessed by Agatston Score and Volume Score using coronary calcium score imaging.
Results: Vessel segments were divided into 5 groups according to Agatston Score: Negative (0), Minimal (1–9), Mild (10–99), Moderate (100–399) and Severe (≥400). Out of 12 Agatston Score negative vessel segments, 75% (9/12) segments demonstrated calcium deposit by OCT with thickness < 1.0mm. However, all Agatston Score positive segments (n=35) got positive Calcium Volume Index by OCT. Out of 13 Minimal/Mild Agaston Score segments, only 23% (3/13) segments had calcium thickness ≥1.0mm. Overall, both Agatston Score and Volume Score showed significant correlation with Calcium Volume Index by OCT (Agatston Score, r=0.84, p<0.01; Volume Score, r=0.83, p<0.01, respectively). When Agatston Score were compared among the different calcium thickness (≤0.5mm, 0.5–1.0mm, ≥1.0mm), Calcium Volume Index of thickness of 0.5–1.0mm demonstrated a better correlation with Agatston Score (≤0.5mm, r=0.48, p<0.01; 0.5–1.0mm, r=0.87, p<0.01; ≥1.0mm, r=0.70, p<0.01, respectively).
Conclusions: OCT has a better sensitivity for detecting coronary artery calcification than MDCT. Both Agatston Score and Volume Score are well correlated to Calcium Volume Index by OCT, especially when calcium thickness is ≥0.5mm.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Interventional Cardiology: Angiography, Intravascular Imaging and Interventional CT/MR
Abstract Category: 16. Interventional Cardiology: Angiography and Interventional CT/MR
Presentation Number: 1153-117
- 2017 American College of Cardiology Foundation