Author + information
- Vijayalakshmi Kunadiana,b,
- Hannah Sinclaira,b,
- Jonathan Battya,b,
- Sophie Z. Gua,b,
- Benjamin Beskaa,b,
- Murugapathy Veerasamya,b,
- Gary A. Forda,b and
- Weiliang Qiua,b
Background: Frailty is common in older patients with non-ST elevation coronary syndrome (NSTEACS) and is associated with a high morbidity and mortality. The influence of frailty on physical quality of life (QoL) outcomes after invasive treatment for NSTEACS was studied.
Methods: Patients aged ≥75 years (n=232) with NSTEACS were enrolled. Frailty was assessed using the Fried criteria, where a score of 0 is robust, 1 or 2 is pre-frail and ≥3 is frail. QoL was evaluated using the Short Form-36 (SF-36) questionnaire (license number QM033917) at baseline and 1 year follow-up. The norm-based Physical Component Score (PCS), an aggregated summary score of the 8 SF-36 subscales, is reported.
Results: Mean age was 81±4 years, (60% male, 88% received invasive treatment). At baseline, 39(16.8%) patients were robust, 123 (53%) were pre-frail and 70 (30.2%) were frail. Increasing frailty was associated with decreased physical QoL at both baseline and 1 year (p<0.001 for both time points). Although all frailty groups saw an increase in mean PCS, this difference was only statistically significant in frail group (robust: 42.4±11.4 to 44.3±12.4, p=0.372; pre-frail: 38.4±11.4 to 41.6±11.7, p=0.117; frail: 27.2±8.1 to 32.9±12.7, p=0.015). In addition, only frail patients who were treated invasively saw this significant increase in PCS between baseline and 1 year.
Conclusions: Although frail older patients with NSTEACS have a poorer physical QoL overall, frailty is associated with a similar or greater improvement from baseline QoL in those who receive invasive treatment.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: PCI for NSTEMI and Complex Patients With Multiple Co-Morbidities
Abstract Category: 19. Interventional Cardiology: Complex Patients/Comorbidities
Presentation Number: 1154-135
- 2017 American College of Cardiology Foundation