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Background: We have reported that the approximate mechanical properties of mitral leaflet tissue can be replicated using multi-material 3D printing. We sought to create multi-material patient-specific replicas of the entire mitral valve (MV) apparatus.
Methods: CT images (systolic and diastolic) of a patient being evaluated for MV surgery were exported into a 3D segmentation software (Mimics, Materialize). The MV anatomy was identified and color-coded using a specifically developed tagging algorithm. These segmented anatomic elements were each coded for 3D printing with a specific color and material (Tango Plus). The model was tested for anatomical accuracy against the CT dataset and used for benchtop MitraClip implantation.
Results: Patient-specific MV apparatus, including annulus, leaflets, chordae and papillary muscles, were 3D printed using tissue-like materials (Figure). Anatomical accuracy of 3D prints was verified, dimensions of characteristic features in 3D prints compared well with CT data dimensions – average difference for chordae length, mitral annulus area, MV anteroposterior and mediolateral diameter were 0.45%, 2.53%, 0.47% and 2.1% respectively. Image segmentation, and 3D print materials were adequate for benchtop simulation of MitraClip procedure.
Conclusions: Accurate patient-specific multi-material MV apparatus replicas can be created from CT images. These 3D models could serve as a clinical tool for planning and simulation of structural heart interventions.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Structural Heart Interventions: Focus on Mitral Valve, Left Atrial Appendage and HOCM
Abstract Category: 24. Interventional Cardiology: Mitral and Structural Heart Disease
Presentation Number: 1156-169
- 2017 American College of Cardiology Foundation