Author + information
- Yunkyeong Cho,
- Hyoung-Seob Park,
- Hyuck Jun Yoon,
- Hyungseop Kim,
- Chang-Wook Nam,
- Seongwook Han,
- Seung-Ho Hur,
- Yoon-Nyun Kim and
- Kwon-Bae Kim
Background: To evaluate the long-term clinical outcomes of fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) strategy compared to intravascular ultrasound (IVUS) guided PCI for intermediate coronary lesions.
Methods: 167 consecutive patients, with intermediate coronary lesions evaluated by FFR or IVUS (FFR guided, 83 lesions vs. IVUS guided, 94 lesions), were included. Cutoff value of FFR in FFR group was 0.80 while that for minimal lumen cross sectional area in IVUS group was 4.0mm2. The primary end point was patient oriented clinical outcome (POCO), defined as a composite of cardiac death, nonfatal myocardial infarction, and any revascularization. The secondary end point was target lesion related outcome (TRO), defined as a composite of target lesion related myocardial infarction and revascularization.
Results: Baseline characteristics were similar in both groups except more multivessel disease and smaller vessel diameter in FFR group. IVUS group underwent revascularization therapy significantly more often (91.5% vs. 33.7%, p<0.001). POCO at 5 years was 12.4% (FFR 10.8% vs IVUS 13.8%, p=ns) and TRO was 8.5% (FFR 9.6% vs IVUS 7.4%, p=ns). Kaplan-Meier survival analysis of POCO and TRO were similar (Figure).
Conclusions: Both FFR guided and IVUS guided PCI strategy for intermediate coronary artery disease were associated with favorable 5 year clinical outcomes. FFR guided PCI reduces the need for revascularization of many of these lesions without additional event.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Interventional Cardiology: Stent Failure Analysis by Intravascuar Imaging
Abstract Category: 23. Interventional Cardiology: IVUS and Intravascular Physiology
Presentation Number: 1193-131
- 2017 American College of Cardiology Foundation