Author + information
- Daiga Saito,
- Ippei Watanabe,
- Rine Nakanishi,
- Mikihito Toda,
- Hideo Amano,
- Ryo Okubo,
- Takayuki Yabe and
- Takanori Ikeda
Background: In patients with ST-segment elevation myocardial infarction (STEMI), left ventricular systolic function (LVSF) is associated with prognosis. In the present study, we sought to examine the clinical implication of left ventricular end-diastolic pressure (LVEDP) in patients with STEMI with or without preserved LVSF.
Methods: We retrospectively analyzed clinical data from 278 STEMI patients undergoing successful percutaneous coronary intervention (PCI) between October 2006 and June 2014. LVEDP and left ventricular ejection fraction (LVEF) were measured after PCI. Preserved LVSF was defined as LVEF>55%. The primary endpoint was major adverse cardiac event (MACE; cardiac death, non-fatal myocardial infarction or hospitalization due to heart failure) at 12 months.
Results: Mean follow up period was 42 months, mean age was 64±12 years, 76% was men. Mean LVEF at admission was 55±11% and median LVEDP was 21mmHg. On Kaplan-Meier analysis, MACE was significantly higher in patients with higher LVEDP, irrespective of LVSF (Fig.1). On Cox proportional hazard analysis after adjusting for confounding factors, LVEDP was an independent predictor of MACE (hazard rate=12.17 (1.60-92.26), P=0.01).
Conclusions: In patients with STEMI, LVEDP predicts outcomes irrespective of LVSF.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Novel Developments in Acute Coronary Syndromes
Abstract Category: 15. Interventional Cardiology: ACS/AMI/Hemodynamics and Pharmacology
Presentation Number: 1194-156
- 2017 American College of Cardiology Foundation