Author + information
- Sudheer Nanduri,
- Khaled Tuwairqi,
- Krishna Velagapudi,
- Abdulfattah Saidi,
- Omar Wever Pinzon,
- Elizabeth Dranow,
- Divya Ratan Verma,
- Rebecca Morris and
- Theophilus Owan
Background: Cardiac Power Index (CPI) is reduced in Heart failure patients with reduced Ejection fraction and is associated with adverse cardiovascular outcomes. Furthermore, Central Fractional Pulse Pressure (FPP) is associated with adverse outcomes in patients with ST-Elevation Myocardial Infarction (STEMI) with or without heart failure. However, the relationship of CPI and FPP in Acute Coronary Syndrome (ACS) patients is unknown.
Methods: We characterized 623 consecutive patients presenting to the University of Utah with ACS between January 1, 2013 and June 30, 2015. We estimated Central FPP using invasively acquired ascending aortic pressure as a ratio of pulse pressure (PP) to mean arterial pressure (MAP) and categorize central FPP into tertiles. We also calculated the Cardiac Power Index (CPI) using echocardiogram obtained within a week of the index cardiac catheterization procedure, and examined the relationship between CPI and central FPP.
Results: We found a significant positive correlation between CPI and central FPP, Pearson =0.28, p=0.036 (Figure). The mean age was 63, 71% were male, with mean BMI of 29, 34% had diabetes, 70% had Hypertension, 57% were smokers, 63% were Dyslipidemic.
Conclusions: In this cohort of ACS patients, central FPP predicted higher cardiac power index. Whether central FPP independently predicts adverse cardiovascular outcomes needs to be examined in larger prospective studies.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Novel Developments in Acute Coronary Syndromes
Abstract Category: 15. Interventional Cardiology: ACS/AMI/Hemodynamics and Pharmacology
Presentation Number: 1194-159
- 2017 American College of Cardiology Foundation