Author + information
- Sahil Agrawal,
- Lohit Garg,
- Tanush Gupta,
- Aakash Garg,
- Abdullah Quddus,
- Pedro Villablanca,
- Nirmanmoh Bhatia,
- Divyanshu Mohananey,
- John Kostis and
- Jamshid Shirani
Background: Transcatheter aortic valve replacement (TAVR) is standard of care for symptomatic severe aortic stenosis in high-risk surgical patients. Gender differences in outcomes of TAVR have been suggested.
Methods: We compared outcomes of TAVR in women (n=4,603) and men (n=4,275) using 2011- 2012 Nationwide Inpatient Sample database.
Results: Compared to men, women were older (mean age 81.8-vs-80.6 years, p<0.001) and had higher rates of hypertension (81%-vs-79%, p=0.01), hypothyroidism (28%-vs-13%, p<0.001), and obesity (15%-vs-11%, p<0.001), but lower rates of renal failure (29%-vs-43%, p<0.001) and peripheral vascular disease (28%-vs-33%, p<0.001). Following TAVR, adjusted rates of all-cause in-hospital mortality (5%-vs-4.3%, p=0.38) and stroke (1.8%-vs-vs-1.1%, p=0.2) were similar between sexes while women had higher rates of vascular (injury, transfusion, and bleeding) and pericardial complications and lower rate of permanent pacemaker implantation during index hospitalization (Table). Women also had longer mean length of hospital stay (8.8-vs- 8.2 days, p<0.001) and more likely to be discharged to a long-term care facility (43.8%-vs-25.5%, p<0.001).
Conclusions: Despite higher age and higher prevalence of co-morbid conditions, women undergoing TAVR experienced similar in-hospital mortality and post-procedure stroke rates. Higher procedural complication rates may account for longer hospital stay and need for skilled facility care following discharge in women.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Interventional Cardiology: TAVR 2
Abstract Category: 17. Interventional Cardiology: Aortic Valve Disease
Presentation Number: 1195-172
- 2017 American College of Cardiology Foundation