Author + information
- Minsu Kim,
- Woong Chol Kang,
- Jeonggeun Moon,
- Pyung Chun Oh,
- Yae Min Park,
- Wook-Jin Chung,
- Youngwoo Jang,
- Jongwook Yu and
- Taehoon Ahn
Background: Patent foramen ovale (PFO) has been recognized as a possible cause of ischemic stroke or transient ischemic attack(TIA). However, randomised trials regarding PFO closure have showed conflicting results. This study was to compare the effectiveness of PFO closure and medication for prevention of recurrent stroke or TIA in highly selected patients (PFO shunt grade more than moderate) with cryptogenic stroke.
Methods: Consecutive 180 patients (men: 135 pts, mean age: 49.9±10.1 year old, closure group: 92 pts, medication group: 88 pts) were enrolled. The primary end point was a composite of recurrent stroke and transient ischemic attack.
Results: Baseline characteristics were similar between the two groups, except age, which was younger in the closure group (47.7±10.4 vs. 52.1±9.3, p=0.004), and shunt at rest or septal hypermobility, which was higher in the closure group (63.0% vs. 23.9%, p=0.000). The device was successfully implanted in all patients in closure group. During follow-up period (mean 28.1 months), primary end point was not different between two groups. However, recurrent stroke was more common in medication group than closure group (5.7% vs. 0%, p=0.026).
Conclusions: Our data showed PFO closure may be benefit in selected patients (shunt grade more than moderate) with cryptogenic stroke in terms of reducing ischemic burden.
Poster Contributions Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Interventional Cardiology: Structural Heart Disease
Abstract Category: 24. Interventional Cardiology: Mitral and Structural Heart Disease
Presentation Number: 1241-142
- 2017 American College of Cardiology Foundation