Author + information
- Yoshifumi Nakajima,
- Krissada Meemook,
- Mamoo Nakamura,
- Asma Hussaini and
- Saibal Kar
Background: Percutaneous mitral valve repair (MVR) using MitraClip system is a novel technique to treat patients with severe mitral regurgitation (MR). There is some literature showing safety and durability of MitraClip procedure for up to 5 years, however, longer durability is unknown. This study serves to evaluate further clinical outcomes and durability of percutaneous MVR with the MitraClip system after 5 years.
Methods: From October 2005 to December 2008, we treated 36 consecutive patients with symptomatic moderate-to-severe or severe MR, using the MitraClip system. Among the 36 patients, 15 patients (mean age at the procedure 63.4 ± 14.9 years, 60% male) who have more than 5 years follow up, were evaluated. Those patients who had surgical treatment, died, or were lost to follow-up, up to 5 years were excluded.
Results: The mean follow-up length was 2996 days (range 1978-3829 days. The Society of Thoracic Surgeons risk of mortality for replacement was 3.78 ± 4.58, and 73% had degenerative MR. Among those 15 patients, 2 cardiac events were observed. One patient needed surgical repair 6 years after the initial procedure, and another patient was re-hospitalized with heart failure at 8 years. No patients died after 5years in this group. There were no specific predictors with these events because of the small number of subjects.
Conclusions: Percutaneous MVR showed effectiveness and durability in long term after 5 years. In the selected patients, percutaneous MVR using MitraClip system appears to be a durable treatment option for severe MR.
Poster Contributions Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Interventional Cardiology: Structural Heart Disease
Abstract Category: 24. Interventional Cardiology: Mitral and Structural Heart Disease
Presentation Number: 1241-145
- 2017 American College of Cardiology Foundation