Author + information
- Salman Atiq Arain,
- Yelin Zhao,
- Jaafer Al-Khafaji,
- Kaleb Lambeth,
- Abhijeet Dhoble,
- Tom Nguyen,
- Pranav Loyalka,
- Biswajit Kar,
- Richard Smalling and
- Prakash Balan
Background: Transcatheter aortic valve replacement (TAVR) via the transapical (TA) route is associated with higher mortality and morbidity compared to the transfemoral (TF) route. We compared the effect of gender on 30-day outcomes following TA and TF TAVR at a single high-volume TAVR center.
Methods: We retrospectively analyzed data for consecutive patients who underwent TA or TF TAVR at our institution between November 2011 and September 2015. Clinical outcomes were compared between men and women in both groups. The primary endpoint was 30-day all-cause mortality; secondary endpoints included stroke, bleeding, new pacemaker, myocardial infarction, and length of stay.
Results: A total of 562 patients underwent TAVR (TF 451 [80.2%], TA 111 [19.8%]) at our institution during the study period (see Table). TA TAVR was associated with a higher risk of 30-day all-cause mortality in the entire cohort (6.4% vs. 2.3%, p=0.057). There was no difference in 30-day mortality after TA TAVR or TF TAVR (3.7 vs. 2.6%, p=0.629) among women (n=254). However, 30-day mortality was significantly higher after TA TAVR in male patients (n=308) (8.9% vs. 2.1%, p=0.024; odds ratio=4.627, 95% CI [1.29-16.58]).
Conclusions: TA TAVR is associated with higher risk of 30-day all-cause mortality compared to TF-TAVR in men; there is no significant difference in 30-day mortality between the two approaches in women.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Interventional Cardiology: TAVR 3
Abstract Category: 17. Interventional Cardiology: Aortic Valve Disease
Presentation Number: 1243-176
- 2017 American College of Cardiology Foundation