Author + information
- Divya Ratan Verma,
- John Spertus,
- Robert Yeh,
- William Lombardi,
- James Sapontis,
- James Grantham and
- Ashish Pershad
Background:. There is limited data regarding the impact of sex on patients’ health status after PCI of a chronic total occlusion (CTO). We compared health status outcomes for women and men undergoing CTO PCI.
Methods: We used data from1000 patients, 804 males and 196 females, in the OPEN CTO study to performed optimal (n:m) propensity score-matching based on age, CTO vessel and J-CTO score and compared health status (and clinical outcomes) of females to males.
Results: A total of 892 patients were included (175 females and 717 males. At baseline, females had a lower Seattle angina Questionnaire (SAQ) quality of life (QoL 44.9 vs 50.1, p=0.01), Physical limitation (PL 55.5 vs 67.1, p<0.001), higher Rose dyspnea scale (RDS 2.6 vs 2, p<0.001) scores. The rate of successful CTO PCI and in-hospital MACCE were similar for females (p=n.s). At 12 months, there was a significant improvement in all scores for both genders (p<0.05). (Figure). The respective change in SAQ PL from baseline to 12 months was higher for females (SAQ PL 31.9 vs 24.6, p=0.004) while other changes in health status scores were similar to males.
Conclusions: Females with CTO are more symptomatic at baseline but derived equal or greater health status benefits than men after PCI. These results support CTO PCI for both females and males to improve health status.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Advances in Chronic Total Occlusion Intervention
Abstract Category: 20. Interventional Cardiology: Coronary Intervention: CTO
Presentation Number: 1282-127
- 2017 American College of Cardiology Foundation