Author + information
- Gaurav Patel,
- Maitri Pancholy,
- Sukrut Nanavaty,
- Neha Pancholy,
- Aman Patel,
- Anvit Rai,
- Mark Sandhaus,
- Tejas Patel,
- John Coppola,
- Tak Kwan and
- Samir Pancholy
Background: Stent thrombosis (ST) is a catastrophic complication with poor outcomes. Temporal trends of the incidence, substrate characteristics and outcomes of stent thrombosis in a real world population are largely unknown.
Methods: The Nationwide Inpatient Sample (NIS) files from 1998 to 2013 were used to extract patient data. All percutaneous coronary intervention (PCI) procedures in patients 18 years of age and older were extracted by using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9- CM) codes for PCI (00.66, 17.55, 36.0, 36.01, 36.02, 36.05, 36.06, 36.07, and 36.09). Patients with a diagnosis of ST were identified by using the ICD-9-CM code (996.72). Temporal trends of incidence of stent thrombosis, patient comorbidities and in-hospital mortality were analyzed.
Results: A total of 120,721,741 patients were hospitalized, of which 2,194,322 patients 18 years of age and older underwent PCI between 1998 and 2013. The incidence of stent thrombosis has marginally but significantly increased over the study period, (0.1% in 1998 to 0.2% in 2013, P trend = 0.0005). The comorbid complexity of patients undergoing PCI increased significantly over the study period (hypertension: from 50.4% to 76.7%, P trend = 0.0005; diabetes: from 23.5% to 40.0%, P trend = 0.0005; chronic kidney disease: from 0.8% to 15.3%, P trend = 0.0005; prior stroke: from 0.9% to 1.2%, P trend = 0.0005; atrial arrhythmia: from 8.3% to 14.0%, P trend = 0.0005; peripheral vascular disease: from 6.1% to 11.7%, P trend = 0.0005). The trend of patients with ST undergoing PCI has remained stable over the analyzed period (35.8% in 1998 to 53.9% in 2013, P trend = 0.127). In-hospital mortality of patients presenting with stent thrombosis decreased over the study period (5.5% in 1998 to 2.8% in 2013, P trend = 0.022).
Conclusions: Despite increasing complexity of PCI patients, the incidence of ST has only marginally increased from 1998-2013, whereas in-hospital mortality in patients presenting with ST has significantly decreased.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Interventional Complexity and Complications
Abstract Category: 26. Interventional Cardiology: Vascular Access and Complications
Presentation Number: 1285-159
- 2017 American College of Cardiology Foundation