Author + information
- Charles Pedlara,b,
- Marcel Browna,b,
- James Ottoa,b,
- Aimee Dranea,b,
- Jennifer Michaud Fincha,b,
- Miranda Contursia,b,
- Robert Shavea,b,
- Meagan Wasfya,b,
- Adolph Huttera,b and
- Aaron Baggisha,b
Background: Deliberate exercise abstinence, “prescribed detraining”, has been proposed as means to differentiate the athlete's heart from occult cardiomyopathy. At present, data defining the myocardial response to detraining among healthy athletes are sparse.
Methods: Marathon runners participated in a structured 18-week training program (∼7-8 h/w) then completed the 2016 Boston Marathon. Participants then reduced total exercise exposure to <2 h/w (no single session >1 hour) for 8 weeks. Exercise testing, echocardiographic, and blood volume measurements were performed 10-14 days before and at 4- and 8-weeks after the marathon. Mixed linear modeling adjusting for age and marathon finish time was used to compare data across time.
Results: Twenty-two runners (age = 34.5 ± 7.5 y, 50% men) completed all aspects of the protocol. Physiologic detraining was confirmed by serial reductions in time to exhaustion during treadmill testing (p<0.01). Myocardial remodeling and hematologic adaptations with a biphasic time course were observed (Figure 1). Plasma volume, left atrial volume, and left ventricular mass and wall thickness, regressed by 4 weeks. In contrast, regression of left and right ventricular chamber size occurred only after 8 weeks of exercise abstinence.
Conclusions: Athletic heart regression during prescribed detraining follows structure specific time courses. Thus, the duration of prescribed detraining should account for the specific clinical question being investigated.
Moderated Poster Contributions
Non Invasive Imaging Moderated Poster Theater, Poster Hall, Hall C
Saturday, March 18, 2017, 12:45 p.m.-12:55 p.m.
Session Title: Hearts and Soles: Multimodality Imaging in Athletes
Abstract Category: 31. Non Invasive Imaging: Sports and Exercise
Presentation Number: 1225M-05
- 2017 American College of Cardiology Foundation