Author + information
- Derek Leong,
- Tamar Aintablian,
- Jignesh Patel,
- Michelle Kittleson,
- Dael Geft,
- Lawrence Czer and
- Jon Kobashigawa
Background: Patients(pts) with end-stage heart disease and renal disease may require combined heart-kidney transplant (HKTx). For donors ≥40 years, a coronary angiogram is often performed to exclude donor coronary artery disease, exposing these older donor kidneys to contrast. Further contrast may be used for imaging of other organs. We sought to assess whether contrast exposure affects donor kidney function in HKTx recipients.
Methods: Between 2010-15 we assessed 47 HKTx pts. They were separated according to whether donors received contrast. Post-HKTx outcomes included GFR (by CKD-EPI) at 1-wk, 1-mth and 6-mths and freedom from dialysis at 6 mths. Delayed graft dysfunction (DGF) defined by need for dialysis ≤7 days of HKTx was also evaluated.
Results: Pts receiving a kidney with contrast exposure were more likely to receive older organs. There was no significant difference in GFR at 1-wk, 1-mth and 6-mths post-HKTx. There was no difference in 6-mth freedom from chronic dialysis or DGF. Donor diabetes was similar in both groups.
Conclusions: Donor contrast exposure prior to HKTx does not appear to compromise post-transplant renal function.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Non Invasive Imaging: Applications in Novel Disease States and Clinical Scenarios
Abstract Category: 27. Non Invasive Imaging: CT/Multimodality, Angiography, and Non-CT Angiography
Presentation Number: 1117-198
- 2017 American College of Cardiology Foundation