Author + information
- Anthony Merlocco,
- Russell Cross,
- Peter Kellman,
- Hui Xue,
- Michael Hansen and
- Laura Olivieri
Background: Myocardial deformation, measured by strain, is an important measure of cardiac function and can be assessed on cardiac magnetic resonance (CMR) breath-held segmented steady-state free precession (SSFP) images. Several free-breathing cine techniques have been validated for volume and function measurements, allowing evaluation of sicker or younger patients. Strain measurements from free-breathing cines have not been validated. We compared global circumferential strain (GCS) measurements from cine imaging acquired by segmented breath-held SSFP (BH), free-breathing averaged SSFP (AVE), and motion-corrected re-binning reconstruction (MOC).
Methods: Thirty-five subjects underwent BH, AVE, and MOC techniques, and an additional 15 underwent just BH and MOC. Global circumferential strain (GCS) and mid-septal strain were measured using commercial software (MEDIS QStrain 2.1). Pearson correlation coefficients tested agreement across techniques.
Results: GCS and mid-septal strain obtained by MOC and AVE SSFP compared favorably to the gold standard BH SSFP (Figs. 1 and 2; p<0.001 for each).
Conclusions: CMR strain analysis provides an important tool to assess myocardial contractility. Strain measurements from free-breathing cines compare favorably to gold standard BH and are more easily obtained, allowing valuable evaluation of sicker or younger patients, or others unable to follow commands.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Non Invasive Imaging: MR Characterization and Function
Abstract Category: 29. Non Invasive Imaging: MR
Presentation Number: 1118-216
- 2017 American College of Cardiology Foundation