Author + information
- Mohamed Morsya,b,
- Teresa Slomkaa,b,
- Anuj Shuklaa,b,
- Dipan Uppala,b,
- Oluwaseun Akinseyea,b,
- Santosh Koshya,b and
- Nadish Garga,b
Background: Although atrial fibrillation (AF) is a common arrhythmia after trauma or burn injury, its predisposing factors are not clearly known. Moreover, little is known on its effect on mortality and other short-term clinical outcomes. This study aimed at identifying the risk factors for new onset AF (NOAF) in patients admitted with trauma or burns, and to determine its effect on short-term clinical outcomes.
Methods: This case control study compared patients with NOAF with a cohort of patients without AF (non-AF) during the hospital stay after trauma or burn injury. Patients with prior AF or lack of transthoracic echocardiogram (TTE) were excluded. This is a case-control study of patients admitted for blunt trauma or burns and new onset AF. Demographic, clinical factors including injury severity score (ISS), and echocardiographic parameters were compared in both cohorts. Risks of short-term clinical outcomes, namely persistent AF, new stroke, myocardial infarction (MI), or death, were compared.
Results: A total of 98 patients, including 48 NOAF and 50 non-AF patients, were studied. The mean age of all patients was 55.6±18.2 years and 68% were males. Baseline characteristics were similar in both cohorts except that the NOAF patients were older (62±16 vs 49±18 years, p=0.0001) and ISS was higher in the non-AF group (36±19 vs 26±15 p=0.03). Older age, sepsis, CHADS2-VASC score >1, larger left atrium (LA) size, left ventricular hypertrophy (LVH), and LV diastolic dysfunction imposed significant risk for new onset AF. On multivariate analysis, independent predictors of NOAF were left atrial dilation (OR—3.8 95% CI -2.3-6.5; p<0.0001), left ventricular hypertrophy (LVH) (OR—8.4 95% CI-3.2-21.8; p<0.0001). Rates of in-hospital mortality, MI, stroke or persistent AF were similar in NOAF and non-AF patients.
Conclusions: Dilated LA and LVH are independent predictors of new onset AF in trauma and burns patients. New onset AF did not confer increased risk for in-hospital short-term clinical outcomes.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Novel Echocardiographic Methods for Assessing Cardiac Function
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1120-240
- 2017 American College of Cardiology Foundation