Author + information
- Vira Ayzenbart,
- Paula Strassle,
- Cassandra Ramm,
- Siyuan Sheng and
- John Vavalle
Background: The extent and distribution of cardiac calcification can impact the treatment of aortic valve stenosis with transcatheter aortic valve replacement (TAVR). An echo-based global cardiac calcium scoring system has been developed and previously validated. However, the relationship between this echo-based cardiac calcium score (eCS) and post-TAVR complications has never been evaluated.
Methods: Patients undergoing TAVR from 11/14 to 5/16 at the University of NC Hospitals were eligible for inclusion. The eCS (range 0-13) was determined using pre-TAVR echocardiograms. Analyzed as a continuous, linear variable, the association between eCS and post-TAVR complications such as permanent pacemaker (PPM), left bundle branch block (LBBB), and paravalvular leak (PVL) were estimated using logistic regression.
Results: A total of 48 patients were included. The median age was 82 (IQR 72-86) with 44% being females, 85% with hypertension, 75% with hyperlipidemia, 85% with CAD, and 38% with diabetes. A one-unit increase in eCS was associated with a significant increase in the odds of permanent pacemaker placement (OR 2.10, 95% CI 1.03, 4.30). An increase in eCS did not significantly change the odds of LBBB or PVL.
Conclusions: This simple echo-based cardiac calcium score appears to be a useful tool in determining which patients are at higher risk of requiring a permanent pacemaker after TAVR. This tool can be easily integrated into the pre-operative risk assessment of patients being evaluated for TAVR.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Emerging Applications of Echocardiography
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1160-226
- 2017 American College of Cardiology Foundation