Author + information
- Christopher B. Link,
- Aditi Nayak,
- Robert Kormos,
- Marc Simon,
- Jeffrey Teuteberg,
- Luigi Lagazzi,
- Andrew Althouse and
- Prem Soman
Background: Pre-LVAD analysis of RV function is critical for surgical planning and determines operative outcome. Current imaging techniques have yielded limited success at predicting RV failure (RVF). GBPS is count based without geometric assumption, and allows global and regional RV function assessment.
Methods: GBPS and hemodynamic data on 34 pre-LVAD patients were prospectively collected. Analyzed GBPS variables included measurements of global function such as right ventricular ejection fraction (RVEF), RV end-diastolic volume (RVEDV), RV end-systolic volume (RVESV), and assessment of regional RV wall motion (RVWM) in the free wall, base, and apex. Regional RVWM for each segment was scored as: 0 – normal, or 1 – abnormal. RVF was defined as the need for RV assist device or greater than 14 days of postoperative inotropes.
Results: All patients had RV function adequately assessed (see Figure). Of 34 patients, 5 (15%) developed RVF. Regional RVWM abnormalities of the free wall occurred more frequently in patients with RVF (100% vs. 52%, p=0.04). Measurements of global systolic function were not associated with RVF. No hemodynamic parameter was associated with RVF.
Conclusions: The ability to determine regional RVWM is an advantage of GBPS over echocardiography and may provide additive prognostic value. The use of GBPS for RV assessment is a new and clinically valuable application of nuclear cardiology.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Nuclear Cardiology: Beyond Perfusion
Abstract Category: 30. Non Invasive Imaging: Nuclear
Presentation Number: 1196-201
- 2017 American College of Cardiology Foundation