Author + information
- Kristoffer Skaarupa,b,
- Hanne K. Christensena,b,
- Nis Hosta,b,
- Maasti M. Mahmouda,b,
- Christian A. Ovesena,b,
- Flemming Javier Olsena,b,
- Jan Skov Jensena,b and
- Tor Biering-Sorensena,b
Background: Asymptomatic paroxysmal atrial fibrillation (PAF) is often assumed to be the cause of the cryptogenic ischemic strokes (IS) or transient ischemic attacks (TIA). We examined whether measures obtained by 2D speckle tracking improves the diagnosis of PAF in patients with IS and TIA.
Methods: We retrospectively included 205 patients who after acute IS or TIA underwent an echocardiogram in sinus rhythm. Patients were designated as PAF-patients if they had one or more reported incidents of AF before or after their echocardiographic examination.
Results: Patients in the PAF group were significantly older (61±13 vs. 52±14 years, p<0.001), had higher CHA2DS2-VASc score (3.8±1.3 vs. 3.3±1.3, p=0.040) and higher National Institutes of Health Stroke Scale (NIHSS) score (3.0±5.0 vs. 1.5±3.4, p=0.028) than patients without PAF. None of the conventional echocardiographic parameters were significantly associated with PAF.
Of the speckle tracking measurements only early diastolic strain rate (0.7 s-1±0.2 vs. 0.8 s-1±0.3, p=0.048) and global longitudinal displacement (GLD) (3.15mm±1.40mm vs 3.87mm±1.56mm, p=0.007) proved significantly different (Figure). Only GLD proved significant after adjustment for age, gender, CHA2DS2-VASc and NIHSS scores (OR=1.34, CI95%[1.02-1.77], p=0.036).
Conclusions: In patients with IS and TIA measurement of GLD is independently associated with the presence of PAF. Applying this may yield better risk stratification for PAF-presence in patients suffering IS and TIA.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Innovative Use of Echocardiography
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1197-210
- 2017 American College of Cardiology Foundation