Author + information
- Alaa Mabrouk Salem Omara,b,
- Allen Weissa,b,
- Sukrit Narulaa,b,
- Megan Cumminsa,b,
- Piedad Lerena Saenza,b,
- Ahmad Mahmouda,b,
- Mohamed Abdel-Rahmana,b,
- Osama Rifaiea,b and
- Partho Senguptaa,b
Background: Speckle tracking echocardiography (STE) derived left ventricular (LV) mechanical variables can vary based upon the severity LV diastolic dysfunction (DD) and filling pressures (LVFP). We sought to investigate the concordance between 2D-Doppler variables of DD suggested in 2016 American Society of Echo (ASE) guideline and those derived from STE.
Methods: Cluster analysis models of LV diastolic function were explored in 130 patients using conventional parameters (Model-C), and their STE correspondents (Model-STE). Models were subsequently tested in 44 patients with invasively measured pulmonary capillary wedge pressure (PCWP).
Results: In the exploratory cohort, a significant overlap was seen between conventional and STE parameters (figure 1a). Model-C yielded 3 clusters with increasing severity of DD and LVFP (figure 1b), while Model-STE yielded only 2 clusters corresponding to Grade 1-2 DD with mild to moderately elevated LVFP and Grade 3 DD with severely elevated LVFP (figure 1c). Both models showed a significant level of agreement (Kappa= 0.56, p<0.001, figure 1d). Similar classifications of patients were produced when Model-C and Model-STE were saved and reapplied to the validation cohort, with a similar level of agreement (Kappa=0.76, p<0.001).
Conclusions: STE based assessment of DD can be used reliably for arriving at 2D-Doppler based classification of DD suggested by 2016 guideline updates.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Innovative Use of Echocardiography
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1197-230
- 2017 American College of Cardiology Foundation