Author + information
- Rachid Abou,
- Laurien Goedemans,
- Rob J. van der Geest,
- Martin Schalij,
- Nina Ajmone Marsan,
- Victoria Delgado and
- Jeroen Bax
Aim: The present study evaluated different scoring parameters of left ventricular (LV) scar tissue on late gadolinium contrast enhanced cardiac magnetic resonance (LGE-CMR) and their impact on multilayer (epi-, mid- and endocardial) LV global longitudinal strain (GLS) in patients after ST-segment elevation myocardial infarction (STEMI).
Methods: Four LV scar scores were calculated on LGE-CMR: 1) spatial extent of scar tissue: number of hyperenhanced segments; 2) transmurality: number of segments with ≥50% transmurality; 3) total scar score: sum of segmental scar scores according to transmurality divided by 17 and, 4) percentage of scar tissue: percentage of LV myocardium with hyperenhancement calculated by signal intensity. Multilayer LV GLS was measured with speckle tracking echocardiography.
Results: 88 STEMI patients (85% male, 57±10 years) were evaluated. On LGE-CMR, spatial extent of scar, transmurality, total scar score and percentage of scar tissue were 7.0±3.8, 1.7±1.8, 0.8±0.5 and 12±9%, respectively. Mean LV GLS at epi-, mid- and endocardium were −12.5±5.6%, −14.2±6.3% and −16.5±7.7%, respectively (p<0.001). On multivariable analysis, percentage of scar was the only parameter independently associated with LV GLS at all layers whereas transmurality was not associated with multilayer LV GLS (Table).
Conclusions: After STEMI, percentage of scar tissue on LGE-MRI reflects more accurately the LV functional consequences on multilayer as compared with other scar scoring parameters.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Non Invasive Imaging: MR Scar and Perfusion
Abstract Category: 29. Non Invasive Imaging: MR
Presentation Number: 1244-198
- 2017 American College of Cardiology Foundation