Author + information
- Qing Shang,
- Hua Li,
- Lai-Shan Tam,
- John E. Sanderson,
- Ching-Han Priscilla Wong,
- Cheuk-Man Yu and
- Brian Tomlinson
Background: Patients with psoriatic arthritis experience a long-term and low-level systemic inflammation with intermittent flare-ups that may affect cardiac function. This study aimed to explore an early impairment of left ventricular longitudinal functional reverse in such patients.
Methods: Left ventricular longitudinal functional reserve indices derived by mitral annular systolic and early diastolic velocities were compared between 60 patients with psoriatic arthritis but without cardiovascular diseases and 27 age-, blood pressure- and gender-comparable control subjects at rest and with a low-level (25 W, 3 min increments) bicycle Ergometer exercise.
Results: Although there was no significant difference in LV structure and function at rest between two groups, the LV longitudinal functional reserve indices at exercise (25W & 50W) in patients were significantly lower than those in control subjects (p<0.05). (Table) Furthermore, the longitudinal reverse indices were negatively correlated with erythrocyte sedimentation rate and Ln(C-reactive protein) (p<0.05).
Conclusions: Patients with psoriatic arthritis had an early impaired left ventricular longitudinal functional reverse, correlating with chronic inflammation. Assessment of longitudinal LV function even on mild exercise can detect early limitations of cardiac function.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Non Invasive Imaging: Role of Exercise Testing
Abstract Category: 31. Non Invasive Imaging: Sports and Exercise
Presentation Number: 1289-205
- 2017 American College of Cardiology Foundation