Author + information
- Hilda Mariana Gonzalez Bonilla,
- Mohamamd Khan,
- Eric Yang,
- Akanksha Thakkar,
- Bader Alshammari,
- Roberto Barrios,
- Faisal Nabi,
- Michael Reardon and
- Dipan Shah
Background: Cardiac magnetic resonance (CMR) has become useful for the non-invasive assessment of cardiac and mediastinal masses in determining if they are malignant and thus may require more aggressive therapies. Current methods rely on qualitative comparisons with myocardium and can still result in diagnostic ambiguity. Our objective was to examine quantitative tissue characteristics of known benign and malignant masses as a premise for objectively classifying them.
Methods: Of 2,835 CMR cases reviewed from 2009 to 2016, 59 patients were found to have pathology reports. Of those 59 patients, 30 with native and post-contrast T1 and T2 characteristic maps were included. ECV was calculated using the lamda partition coefficient derived from the native and post-contrast T1 maps, and hematocrit.
Results: The patients were divided in 2 groups (Table). Basic characteristics as hypertension, dyslipidemia, diabetes, history of tobacco use, family history of coronary artery disease or sudden cardiac death were not significantly different. Native T1 relaxation time values of the masses were significantly higher in benign versus malignant masses (p<0.01) but were not significantly different for T2 relaxation times (p=NS), post-contrast T1 times (p=NS) and extracellular volume fraction (ECV; p=NS) of the masses (Table).
Conclusions: Native T1 mapping may be useful for differentiating benign versus malignant cardiac and mediastinal masses on CMR.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Non Invasive Imaging: MR Structure and Valuvular Heart Disease
Abstract Category: 29. Non Invasive Imaging: MR
Presentation Number: 1290-208
- 2017 American College of Cardiology Foundation