Author + information
- Alwin Zweerink,
- Cornelis Allaart,
- Joost P.A. Kuijer,
- Lina Wu,
- Aernout Beek,
- Peter van de Ven,
- Mathias Meine,
- Piere Croisille,
- Patrick Clarysse,
- Albert van Rossum and
- Robin Nijveldt
Background: Although myocardial segmental strain analysis is a potential tool to improve the patient selection for Cardiac Resynchronization Therapy (CRT), currently a well validated clinical approach to derive segmental strains is lacking. This study evaluates a novel method of segment length tracking (SLT) to derive segmental strain measures from standard CMR cine images in CRT candidates.
Methods: Twenty-seven patients (age 65±10 y, 16 men) with left bundle branch block underwent CMR cine imaging and myocardial tagging (MT) imaging to assess segmental strains in the septum and the lateral wall. SLT was performed by measuring segment length between two anatomic landmarks (trabeculae) throughout all phases on short-axis cine images (figure A). This measure of frame-to-frame segment length change was compared to MT circumferential strain measurements (figure B).
Results: Segmental strains in the septum and the lateral wall showed good to excellent agreement between the SLT and MT technique (ICC 0.76 and ICC 0.66, respectively). Conventional markers of CRT response also showed close agreement (SRS, ICC 0.70; SSI, ICC 0.78; and ISF, ICC 0.61). Reproducibility of SLT was excellent for intra-observer testing (all ICC ≥0.76) and good for inter-observer testing (all ICC ≥0.61).
Conclusions: The SLT post-processing technique on standard CMR cine images offers both accurate and robust segmental strain measures compared to the ‘gold standard’ MT technique, with the advantage of being widely available.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Non Invasive Imaging: MR Structure and Valuvular Heart Disease
Abstract Category: 29. Non Invasive Imaging: MR
Presentation Number: 1290-213
- 2017 American College of Cardiology Foundation