Author + information
- Konomi Sakata,
- Aoi Isaka,
- Youichiro Uesugi,
- Mitsufumi Furuya,
- Mayumi Fukushima,
- Kenichi Matsushita,
- Toru Satoh and
- Hideaki Yoshino
Background: In patients with pulmonary artery hypertension (PAH), right ventricular (RV) pressure overload causes right heart failure (RHF). Two-dimensional echocardiographic (2DE) assessment of RV function is limited due to the unique geometry of RV chamber. Recently, a novel three-dimensional speckle-tracking echocardiographic (3D-STE) system specialized for the RV (RV-Wall-Motion-Tracking) was developed. To investigate whether a novel 3D-STE could evaluate the severity of RV dysfunction and prognosis in patients with PAH.
Methods: We performed a novel 3D-STE and right heart catheterization in 102 PAH patients (age: 43±15 years). Quantitative analysis of 3D-STE was performed using RV-Wall-Motion-Tracking (Toshiba Medical Systems) and measured Global RV-Area change ratio (ACR) and segmental ACR in seven RV segments. We performed right heart catheterization (RHC), and measured mean pulmonary artery presuure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI).
Results: Global-RV-ACR correlated with pulmonary vascular resistance (PVR) (r=0.746, p<0.001),3 D-RVEF (r=0.64, p<0.001), mean pulmonary atrial pressure (r=0.62, p<0.001), cardiac index (r=0.68, p<0.001), and BNP (r=0.68, p<0.001) in PAH patients. During 3 years, 19 patients had cardiac death. Global-RV-ACR<-19.8 was a independent predictor of cardiac death.
Conclusions: A novel RV-Wall-Motion-Tracking is useful to evaluate RV dysfunction and prognosis in patients with PAH, noninvasively and quantitatively.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Insights From Echocardiography Use
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1291-219
- 2017 American College of Cardiology Foundation