Author + information
- Marcio Sommer Bittencourta,b,
- Raphael M. Ritti-Diasa,b,
- Aline Geragea,b,
- Gabriel G. Cucatoa,b,
- Raquel Conceicaoa,b and
- Raul Santosa,b
Background: Physical activity has been recommended as a non-pharmacological approach for nonalcoholic fatty liver disease (NAFLD) patients, but its effect in preventing and treating this disease is not well established. The purpose of this study was to analyze the impact of physical activity levels on the occurrence of nonalcoholic fatty liver disease (NAFLD).
Methods: The sample included 5860 subjects evaluated at baseline and after a follow up time – 31 (19-50) months. Subjects were stratified according to ultrasonographic results as with NAFLD (n = 1902; 44.8 ± 8.6 years) or without NAFLD (n = 3958; 41.3 ± 8.6 years) at baseline.
Results: At follow-up subjects were divided according to changes in physical activity levels (remained inactive, became inactive, became active and remained active). Individuals without NAFLD that became or remained physically active were less likely to develop NAFLD compared with those who remained physically inactive, even after adjustments for confounding (OR = 0.75; P = 0.04, and 0.75; P = 0.03, respectively). Among those with NAFLD at baseline, becoming and remaining physically active reverted NAFLD status after initial adjustment for confounding (OR = 0.64; P = 0.01, and 0.66; P = 0.01, respectively), however, this result lost significance body mass index was included in the model (P > 0.05).
Conclusions: Higher physical activity levels are associated with a reduction in the incidence of NAFLD at follow up. In individuals with NAFLD, increase in PALs associated with a reversal of this process, probably mediated by changes in body mass index.
Moderated Poster Contributions
Prevention Moderated Poster Theater, Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-9:55 a.m.
Session Title: Physical Activity and Prevention of Cardiometabolic Disease: Exercise Is Medicine
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1210M-03
- 2017 American College of Cardiology Foundation