Author + information
- Sanjay Nandkoemar Gobardhan,
- Pranobe Oemrawsingh and
- Martin J. Schalij
Background: South Asians (SAs) have one of the highest mortality rates in cardiovascular (CV) disease in the Western world. In this study 10-year incidence rates of CV events were assessed in asymptomatic SAs and compared with a native Dutch Caucasian population.
Methods: In 2004 a cross-sectional study was performed in SAs and compared with Caucasians. At baseline patients were aged 18-59 years, without known hypertension, dyslipidemia, diabetes or CV disease. In 2015 ten-year follow up was completed by a short questionnaire, including CV events as main outcome verified by medical hospital records. Incidence rates were standardized for age and gender using the SA population as standard population.
Results: Ten-year follow up was completed in 504 SAs (age 39.4 ± 10.9 years, 42% male) and 177 Caucasians (age 44.0 ± 9.0 years, 20% male). After 10-year follow up hypertension had the highest prevalence in both populations (23.0% in SAs vs 8.9% in Caucasians, p<0.001), followed by dyslipidemia (22.0% in SAs vs 6.7% in Caucasians, p<0.001). During ten-year follow-up, 30 (6.0%) CV events occurred in SAs aged >18 years at baseline and 5 (3.1%) in Caucasians aged >40 years at baseline, p=0.10 (Fig 1).
Conclusions: In conclusion, young third to seventh generation SA descendants had high rates of hypertension, dyslipidemia, diabetes and CV events at a relatively young age compared with Caucasians. This study highlights the importance of aggressive primary prevention for CV disease in young SA descendants in the Netherlands.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Current Issues in Cardiovascular Epidemiology, Disparities, and Safety
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1148-050
- 2017 American College of Cardiology Foundation