Author + information
- Srikanth Yandrapalli,
- Gabriela Andries,
- Viswajit Reddy Anugu,
- Zeeshan Solangi,
- Sohaib Tariq,
- Pratik Mondal,
- Venkat Lakshmi Kishan Vuddanda,
- Wilbert Aronow,
- Sachin Sule,
- Howard Cooper and
- Savneek Chugh
Background: In the modern dialysis era, uremic and dialysis pericarditis (UDP) are less frequently encountered in clinical practice. We sought to determine the secular variation and in-hospital outcomes of UDP.
Methods: Using the U.S. Nationwide Inpatient Sample databases 2003 through 2012, we pooled a weighted sample of patients with UDP by identifying hospitalizations in patients ≥ 18 years of age, with the primary or secondary diagnoses of acute pericarditis (ICD-9 code 420.0) and renal dysfunction (acute kidney injury (AKI), end stage renal disease (ESRD), and uremia). Hospitalizations with a primary or secondary diagnoses for other types of pericarditis, including bacterial, fungal, protozoal, rheumatic, and viral, were excluded. Associated type of renal dysfunction, type of dialysis modality, pericardial procedures, and outcomes were then analyzed.
Results: A total of 13,003 hospitalizations (mean patient age 55 ± 18 years, 41.4% female) were identified with diagnoses suggestive of UDP. From 2003 to 2012, the prevalence of UDP increased from 13.5 to 47.1 per 1 million hospitalizations (Ptrend<0.005). ESRD was present in 8,852 (68.1%) of these cases, followed by AKI in 4,925 (37.9%) cases. A total of 9,650 (74.2%) cases received hemodialysis and 492 (3.8%) received peritoneal dialysis during the hospitalization. Pericardial procedures were performed in 16.8% of cases, including pericardiocentesis (9.5%), pericardiotomy (8.6%), pericardial biopsy (2.3%), and pericardiectomy (0.7%). Procedure rates were similar for patients with and without ESRD. All-cause inpatient mortality was 6.4%, a decreasing trend from 17.03% in 2003 to 4.43% in 2012 (Ptrend<0.005). Median length of stay was 7 days, and median total hospital charges were US$ 48,673.
Conclusions: Between 2003 and 2012, the prevalence of UDP among all hospitalizations in the United States increased, while the in-hospital mortality rate decreased. Pericardial procedures were common in UDP patients, with almost one-sixth of the cases having a pericardial procedure.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Current Issues in Cardiovascular Epidemiology, Disparities, and Safety
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1148-052
- 2017 American College of Cardiology Foundation