Author + information
- Tasnim F. Imran,
- Jiaying Chen,
- Senthil Selvaraj,
- Ariela Orkaby,
- J. Michael Gaziano and
- Luc Djousse
Background: Walking pace is increasingly being used to assess functional status in ambulatory settings. We sought to prospectively examine whether walking pace is associated with mortality and incident cardiovascular disease (CVD).
Methods: Walking pace was self-reported in a validated questionnaire. Mortality and incident CVD (fatal or nonfatal myocardial infarction, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty and stroke) were ascertained via medical records and adjudicated by the PHS endpoint committee.
Results: We studied 21,926 participants from the Physicians’ Health Study with a mean age of 67.7 ± 9.0 years. After a median follow-up of 8.9 years (IQR: 7.8-10.2), 2,774 deaths and 2,488 incident CVD events occurred. In a multivariable Cox proportional hazards model adjusting for age, race, smoking, alcohol use, caloric intake, walking time, exercise, and prevalence of heart failure, peripheral vascular disease, cancer, renal disease and pulmonary disease, hazard ratios for mortality were 1.12 (95% CI: 0.95-1.32) for a walking pace of <2mph, 0.74 (0.63-0.86) for a walking pace of 2-2.9mph, 0.64 (0.53-0.78) for a walking pace of 3-3.9mph and 0.47 (0.30-0.74) for a walking pace of ≥4mph compared to the group that reported not walking regularly (p trend <0.0001). Similar findings were observed for incident CVD (Table 1).
Conclusions: We found that walking pace is inversely associated with risk of mortality and cardiovascular disease among US male physicians.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Updates on Risk Factors for Cardiovascular Disease
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1187-048
- 2017 American College of Cardiology Foundation