Author + information
- Edita Piacková,
- Bernhard Jäger,
- Serdar Farhan,
- Günter Christ,
- Wolfgang Schreiber,
- Franz Weidinger,
- Thomas Stefenelli,
- Georg Delle-Karth,
- Alfred Kaff,
- Gerald Maurer and
- Kurt Huber
Background: Data obtained from registries have shown that women diagnosed with STEMI are older, have more co-morbidities and a worse clinical outcome than men. Aim of this study was to investigate potential gender differences in in-hospital and long-term mortality in patients from Vienna STEMI registry (2003-2009).
Methods: Data from 4593 patients who were enrolled from January 2003 until December 2009 into the Vienna STEMI registry were analyzed. Gender-related differences in patient characteristics, time delays, reperfusion therapy, as well as short- and long-term all-cause mortality were investigated. A landmark analysis was performed to assess long-term all-cause mortality in patients after discharge. Multivariate regression analysis was performed in order to correct for confounders.
Results: Mean age, history of hypertension, diabetes mellitus, and shock at presentation were significantly higher in women compared to men, whereas men were more frequently smokers, had more frequently a positive family history and a history of previous myocardial infarction. Overall the only significant difference in time delays was found in the onset of pain-to first medical contact time, which was significantly prolonged in women. Unadjusted in-hospital mortality, long-term mortality and long-term mortality for in-hospital survivors were statistically higher for women. Multivariate analysis after adjustment for confounders revealed no differences between genders for in-hospital mortality, long-term mortality, as well as long-term mortality of hospital survivors, respectively.
Conclusions: The higher risk profile and the prolonged delay between onset of pain-to-first medical contact are responsible for the higher unadjusted mortality rates in women versus men. This difference in short and long-term mortalities is no more existent after statistical correction for confounders such as age, co-morbidities and significantly different time delays.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Cardiac Arrest, Diabetes, and Other High Risk Features of Patients With Acute Coronary Syndrome
Abstract Category: 2. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1204-334
- 2017 American College of Cardiology Foundation