Author + information
- Hyung Oh Kim,
- Kim Kwon Sam,
- Weon Kim,
- Jong-Shin Woo,
- Woo-Shik Kim,
- Soo-Joong Kim,
- Jin-Bae Kim,
- Jung Myung Lee,
- Hyemoon Chung and
- Jae Min Kim
Aim: The purpose of the study was to investigate the incidence of subclinical atherosclerosis by coronary artery calcium(CAC) score and atherosclerotic cardiovascular disease(ASCVD) risk score in patients with resistant hypertension.
Methods: For 8823 subjects taking one or more antihypertensive were screened in a single center between January, 2012 and December, 2012,(Figure) the prevalence of resistant hypertension was calculated which was defined as uncontrolled blood pressure above goal despite adherence to a combination of at least three optimally dosed antihypertensive medications, including one of a diuretic. The CAC score and ASCVD risk score was compared in controlled and uncontrolled patients with three or more antihypertensives.
Results: 1410 patients (662 males, 65 ± 12 years old) were treated by three or more antihypertensives. The ASCVD risk score could be calculated only 812 patients (57%). The main reasons of uncalculated ASCVD was out-ranged lipid profile (373 patients), age (178 patients) and systolic blood pressure (47 patients). Among 1410 patients, 367 (4%) were defined as resistant hypertension. The CAC score (244 ± 172 vs 453 ± 212, p=0.04) and ASCVD risk score (19 ± 14 vs 24 ± 17, p<0.01) were significantly different in patients with controlled and resistant hypertension patients.
Conclusions: Patients with resistant hypertension showed more prominent subclinical atherosclerosis, but current ASCVD risk score could not fully assess the risk of subclinical atherosclerosis.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Markers of Prognosis Associated With Elevated Blood Pressure
Abstract Category: 33. Prevention: Hypertension
Presentation Number: 1234-033
- 2017 American College of Cardiology Foundation