Author + information
- Dimitrios Terentes-Printzios,
- Charalambos Vlachopoulos,
- George Andrikopoulos,
- Stylianos Tzeis,
- Efstathios Iliodromitis,
- Dimitri Richter,
- Athanasios Pipilis,
- Dimitrios Stakos,
- David Symeonidis,
- John Lekakis,
- Dimitris Tousoulis and
- Panagiotis Vardas
Background: Guidelines suggest use of cardiovascular risk categories and high intensity statins for patients with acute coronary syndromes (ACS). We examined the risk of ACS patients prior to the event, as well as the overall use and intensity of statins.
Methods: We enrolled 687 ACS patients (mean age 63 years, 78% males). Low-density lipoprotein cholesterol (LDL-c) levels upon admission were used to assess attainment of LDL-c targets. Patients were categorized as very high, high, moderate and low risk based on their prior to admission cardiovascular risk. We examined statin use and dosage intensity among patients discharged. Patients were followed for 189 days.
Results: The majority of the patients (n=371, 54%) were in very high risk prior to admission, while 101 patients had high risk (15%), 147 (21%) moderate risk and 68 (10%) low risk. Interestingly, LDL-c target attainment decreased as the risk increased (p<0.001). The majority (96%) of patients received statins at discharge; however, most of them (60.4%) received low/moderate intensity statins and just 35.9% received the suggested by the Guidelines high intensity dose of statins. At follow-up, rate of patients at high intensity dose of statins remained similar (34.8%). 6% received no statins at all at follow-up.
Conclusions: The majority of ACS patients are already at high risk prior to their admission. Further, LDL-c targets are underachieved prior to the event and high-intensity statins are underutilized in ACS patients at, and post-discharge.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Innovations in Cardiovascular Risk Assessment and Reduction
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1235-041
- 2017 American College of Cardiology Foundation