Author + information
- Hyung Oh Kim,
- Weon Kim,
- Jong-Shin Woo,
- Kwon Sam Kim,
- Woo-Shik Kim,
- Soo-Joong Kim,
- Jin-Bae Kim,
- Jung Myung Lee,
- Hyemoon Chung and
- Jae Min Kim
Background: The coronary artery calcium (CAC) and aortic arch calcification (AoAC) are individually associated with cardiovascular disease and outcome.
Methods: A total of 2,018 stable angina patients who underwent chest X-ray and cardiac multi-detector computed tomography were followed up for 4 years to assess adverse events, which were categorized as cardiac death, stroke, myocardial infarction, or repeated revascularization. The extent of AoAC on chest X-ray was graded on a scale from 0-3.
Results: During the 4 years of follow-up, 620 patients were treated by coronary stenting and 153 (7%) adverse events occurred. A progressively higher grade of AoAC was associated with a higher CAC score or FRS. Cox regression showed that the FRS and CAC score, but not AoAC, were associated with adverse events. In patients with a FRS < 20 or a CAC score < 400, AoAC showed an additive predictive value for detecting significant CAD. A gradual increases in the risk of adverse events were noted if AoAC was present in patients with similar CAC score or FRS (Figure).
Conclusions: Although the CAC score is a powerful predictor of adverse events, evaluation of AoAC could be valuable for predicting significant CAD in low- to intermediate-risk probability patients assessed by FRS.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Innovations in Cardiovascular Risk Assessment and Reduction
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1235-044
- 2017 American College of Cardiology Foundation