Author + information
- Irmina Gradus-Pizloa,b,
- Abhishek Khemkaa,b,
- Richard Kovacsa,b,
- Wanzhu Tua,b,
- Ross Haydena,b,
- Abdullah Masuda,b,
- George Eckerta,b and
- William Tierneya,b
Background: Guidelines recommend intervention on symptomatic, severe mitral regurgitation (MR) and monitoring for less than severe MR. We used clinical data repositories (CDR) to evaluate survival, comorbidities and healthcare utilization in patients who had moderate, moderately severe and severe MR on echo (MR group) compared to patients who had echo with mild or no MR (EC group) and patients who did not have echo (NEC group).
Methods: The search of 2010-2015 echo database identified 1,067 patients with MR. CDR matched MR group with two control groups matched for age, race and gender EC (n=1068) and NEC (n=1066). The analysis was performed using Cox model analysis with interactions.
Results: The MR group had 70% of patients with moderate MR, 20% with mod-severe MR and 10% with severe MR. Patients with MR had significantly lower survival probability compared to EC and NEC control populations (Fig 1). Mortality was similar for patients with moderate, moderate to severe or severe MR. There was significant difference between average EF (MR 43.1%, EC 54.3%, NEC 59%; p=<.0001) and heart failure (MR 64%, EC 37%, NEC 9%, p=<.0001). The MR group was responsible for 23,847 inpatient encounters of which 12,055 were due to HF or HF plus other heart disease. MR group had 2.5 higher rate of healthcare utilization than NEC control.
Conclusions: Patients with moderate MR have as poor survival and high utilization rates as patients with severe MR. Patients with moderate MR may benefit from more aggressive treatment at an earlier stage.
Moderated Poster Contributions
Valvular Heart Disease Moderated Poster Theater, Poster Hall, Hall C
Friday, March 17, 2017, 11:45 a.m.-11:55 a.m.
Session Title: Novel Determinants of Outcomes in VHD
Abstract Category: 36. Valvular Heart Disease: Clinical
Presentation Number: 1132M-17
- 2017 American College of Cardiology Foundation