Author + information
- Claudia See,
- Paul Sorajja,
- Kevin Harris,
- Robert Farivar,
- Richard Bae,
- Matthew Dulas,
- Ross Garberich and
- Mario Gössl
Background: For asymptomatic patients with severe mitral regurgitation (MR), national practice guidelines (GL) recommend serial evaluations every 6 to 12 months for clinical monitoring. However, the impact of adherence to these GL is unknown.
Methods: We examined 184 patients (69±15 yrs; 51% men) with asymptomatic, severe MR who were seen at our institution. Adherence to GL was defined as having serial clinical evaluations with echocardiography within 12±1 months. Comparisons were performed for adherent and non-adherent patients for death and heart failure hospitalization.
Results: During a median length follow up of 809 days (IQR, 808), there were 23 deaths, 96 mitral valve surgeries, and 49 heart failure hospitalizations. Comparing GL-adherent (n=129) and non-adherent patients (n=55), there was no statistically significant difference in survival free of death or heart failure hospitalization (Figure). Patients who were adherent were more likely to receive an intervention compared to non-adherent patients (65.9% [85/129] vs. 20.0% [11/55]; p<0.001). Overall, the median (IQR) time to intervention was 133 (365) days. The median time to intervention was shorter in patients who were adherent compared to non-adherent patients (119 [IQR, 219] days vs. 920  days; p<0.001).
Conclusions: In patients with asymptomatic, severe MR, GL-adherence was not associated with a significant improvement in clinical outcomes, but led to more frequent and earlier interventions.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Valvular Heart Disease: Mitral Valve Disease
Abstract Category: 36. Valvular Heart Disease: Clinical
Presentation Number: 1145-032
- 2017 American College of Cardiology Foundation