Author + information
- Vincent Gacad,
- Ricardo Bellera,
- Ignacio De Cicco,
- Yelin Zhao,
- Fiorella Llanos-Chea,
- Cameron McBride,
- Biswajit Kar,
- Prakash Balan,
- Richard Smalling,
- Igor Gregoric,
- Pranav Loyalka,
- Tom Nguyen and
- Abhijeet Dhoble
Background: While female gender and diabetes mellitus have been shown to be independent risk factors for poorer surgical outcomes in surgical aortic valve replacement, there is a shortage of data on the effect of gender and DM on Transcatheter Aortic Valve Replacement (TAVR). This study examines gender and diabetes mellitus as predictors of post-operative outcomes after TAVR.
Methods: Prospective data was collected over 3 years on 436 consecutive patients undergoing TAVR at our institution. Patients were stratified into four groups by presence of a previous diagnosis of diabetes and by gender. Primary outcomes were 30-day and 1 year mortality; secondary outcomes were major post-operative in-hospital events. Bonferroni correction was used to account for multiple comparisons.
Results: Diabetic females had significantly reduced 1-year mortality compared to diabetic males (7.5% vs 23.8%, p=0.027) and among all groups (p=0.016). No difference in 30-day mortality and post-operative complications was seen. Among non-diabetics, no difference in clinical outcomes was seen between genders.
Conclusions: Diabetic females were shown to have a long-term mortality benefit compared to diabetic males and non-diabetic patients, regardless of gender.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: The Challenges of Outcome Prediction in Valvular Heart Disease
Abstract Category: 37. Valvular Heart Disease: Therapy
Presentation Number: 1274-031
- 2017 American College of Cardiology Foundation