Author + information
- Robert S. Rosenson,
- Michael Farkouh,
- Matthew Mefford,
- Vera Bittner,
- Todd Brown,
- Ben Taylor,
- Keri Monda,
- Hong Zhao,
- Yu Ling Dai and
- Paul Muntner
Background: In 2011, atorvastatin became generic, and in 2013, the ACC/AHA cholesterol guidelines recommended high-intensity statins for patients with acute coronary syndromes. We assessed high intensity statin use before and after these two events.
Methods: We examined secular trends in high-intensity statin use following hospital discharge for myocardial infarction (MI) from 2011 through 2014 among patients 19 to 64 years with commercial health insurance in the Marketscan database (n=42,893) and Medicare beneficiaries ≥66 years (n=151,888). Patients were included if they filled a statin within 30 days following hospital discharge. High-intensity statins included atorvastatin 40 or 80 mg and rosuvastatin 20 or 40 mg.
Results: In the overall population, the percentage of beneficiaries whose first statin fill following hospital discharge for MI was for a high-intensity dose increased from 33.5% to 71.7% in Marketscan, and from 21.8% to 52.4% in Medicare (Figure). Increases in high intensity statin use occurred among patients initiating treatment and those taking low/moderate intensity statins prior to hospitalization. Patients filling antiplatelet therapy and attending cardiac rehabilitation following discharge were more likely to fill a high-intensity statin.
Conclusions: An increase in high-intensity statins between 2011 and 2014 coincided with the generic availability of atorvastatin. The publication of the ACC/AHA guidelines did not appear to impact this trend substantially.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Acute Coronary Syndromes, Diagnosis, Management and Outcomes
Abstract Category: 2. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1253-335
- 2017 American College of Cardiology Foundation