Author + information
- Ryota Kakizaki,
- Yoshiyasu Minami,
- Takehiro Hashikata,
- Teruyoshi Nemoto,
- Kazuhiro Fujiyoshi,
- Sayaka Namba,
- Takuya Hashimoto,
- Tomoyoshi Yanagisawa,
- Kentaro Meguro,
- Takao Shimohama,
- Taiki Tojo and
- Junya Ako
Background: Current strategy of drug eluting stent (DES) implantation is based on the concept of plaque full coverage. However, the coverage status of struts on normal segment beyond the plaque length has not been fully evaluated.
Methods: A total of 1520 stent edge struts in 20 zotarolimus-eluting stents (ZES) were assessed by optical coherence tomography (OCT) imaging within three months follow-up. Neointimal coverage was assessed within 5mm from each stent edge on cross sectional OCT images at every 1mm interval. All well apposed stent struts were classified into normal segment group or lipid plaque group based on the underlying morphologies.
Results: Overall rate of covered struts was 58.4 ± 4.6 % in the edge. The coverage rate was significantly lower in the normal segment group than that in the lipid plaque group (47.7 ± 5.5 % vs 72.4 ± 4.9 %, p<0.01) (Figure). There was no significant difference in the rate of covered struts on normal segment between proximal edge and distal edge.
Conclusions: Struts on normal segment were less covered than those on lipid plaque in the edge within three months after ZES implantation. The caution should be exercised when implanting longer DES to achieve uniform strut coverage in early phase.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Antiplatelet and Antithrombotic Agents in Ischemic Heart Disease
Abstract Category: 3. Acute and Stable Ischemic Heart Disease: Therapy
Presentation Number: 1296-315
- 2017 American College of Cardiology Foundation