Author + information
- Jeanette Ting,
- Li-Ling Tan,
- Iswaree Balakrishnan,
- Aruni Seneviratna,
- Mark Chan,
- Mark Richards,
- Bee-Choo Tai,
- Lieng Ling and
- Chi-Hang Lee
Background: Optimal timing for sleep study in patients presented with acute myocardial infarction (AMI) remains unknown. We determined the prevalence and evolution of obstructive sleep apnea (OSA) and central sleep apnea (CSA) following AMI.
Methods: 397 patients admitted with AMI were recruited prospectively for a sleep study within 5 days of admission. A subgroup of 102 patients admitted with the first AMI underwent a repeat sleep study at 6 months to determine the evolution.
Results: The prevalence of OSA and CSA was 42% (n=166) and 10% (n=39), respectively. Compared with the non-sleep apnea group (n=192), the OSA and CSA groups were older, had a higher body mass index and prevalence of hypertension, and were more likely to receive beta-blocker and angiotensin converting enzyme inhibitor on discharge (p<0.05 for all). The CSA group had a lower left ventricular ejection fraction (45±13%) than the OSA (51±9%) and non-sleep apnea (51±9%) group (p=0.004). The evolution of OSA, CSA, and non-sleep apnea is shown in the figure. Despite the lack of significant change in body mass index (mean difference 0.05, 95% CI −0.16 to 0.27, p=0.614), 46% of the patients in the OSA group had become non-sleep apnea, 83% of the CSA had evolved to OSA, and 93% of the non-sleep apnea remained unchanged.
Conclusions: About half of the patients had either OSA (42%) or CSA (10%) during acute phase of AMI. While sleep study during this phase was effective in ruling out sleep apnea, there was significant evolution of OSA and CSA at 6-month follow-up.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Unusual Presentations of ACS
Abstract Category: 2. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1297-335
- 2017 American College of Cardiology Foundation