Author + information
- Hideki Wadaa,b,
- Tomotaka Dohia,b,
- Katsumi Miyauchia,b,
- Shuta Tsuboia,b,
- Manabu Ogitaa,b,
- Takatoshi Kasaia,b,
- Satoru Suwaa,b and
- Hiroyuki Daidaa,b
Background: Malnutrition has been identified to be one of the most important predictor of worse clinical outcomes in patients with heart failure. However, the prognostic impact of nutrition status in patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) is poorly understood.
Methods: We evaluated the impact of nutrition, using the geriatric nutritional risk index (GNRI) in 2853 patients with CAD who underwent their first PCI between 2000 and 2011. Patients were assigned to tertiles based on their GNRI levels. We evaluated the incidence of major adverse cardiac events (MACE), including all-cause death and acute coronary syndrome (ACS).
Results: During the median follow-up period of 7.4 years, Kaplan-Meier curves showed ongoing divergence in rates of MACE among tertiles (GNRI <98: 45.0%, 98-104: 30.5%, ≥104: 20.8%; log-rank p<0.0001). Stratification analysis by age also revealed that lowest GNRI tertile was significantly associated with MACE in both patients <65 years and ≥65 years. After adjusting for established cardiovascular risk factors including age, ACS, and CKD, lower GNRI was an independent predictor of adverse cardiac events (HR 1.04 per 1 decrease, 95%CI 1.03-1.06, p<0.0001).
Conclusions: The nutrition status evaluated by GNRI was associated with long-term clinical outcomes in patients with CAD after undergoing PCI. GNRI could be a useful and effective predictive marker for adverse cardiac events in almost all ages CAD patients.
Moderated Poster Contributions
Acute and Stable Ischemic Heart Disease Moderated Poster Theater, Poster Hall, Hall C
Sunday, March 19, 2017, 10:15 a.m.-10:25 a.m.
Session Title: CAD in Unique Patient Populations
Abstract Category: 2. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1309M-07
- 2017 American College of Cardiology Foundation