Author + information
- Maria Tomasdottir,
- Leif Friberg,
- Ziad Hijazi,
- Johan Lindbäck and
- Jonas Oldgren
Background: In patients with atrial fibrillation (AF) the risk of stroke is commonly assessed with the CHA2DS2-VASc score. Studies have shown conflicting results regarding risks with low scores. The purpose of this study was to investigate the risk of stroke or systemic embolism associated with each component of the CHA2DS2-VASc score separately in women and men with AF not receiving oral anticoagulation treatment.
Methods: The cohort consisted of adult subjects identified by first contact with a diagnosis of AF in The Swedish National Patient Register between Jan 1, 2006 and Dec 31, 2014. Subjects receiving oral anticoagulation or with valvular AF were excluded. Endpoint was the first occurrence of ischemic or unspecified stroke or systemic embolism.
Results: We identified 34,742 patients with only one CHA2DS2-VASc risk factor beyond sex. Median age was 77 years (range 18-104), 47.3% were women and mean follow-up 3.3 years. The figure depicts incidence rates with 95% confidence intervals of stroke or systemic embolism in relation to individual components of the risk score.
Conclusions: The risk of stroke or systemic embolism is low in both women and men with AF and either heart failure, hypertension, diabetes or vascular disease. Age 65-74 is associated with higher stroke risk than the other CHA2DS2-VASc factors allotted 1 point, but still with similar risk for women and men. In AF patients ≥75 years or with a history of stroke, the risk for stroke or systemic embolism is higher in women than in men.
Moderated Poster Contributions
Arrhythmias and Clinical EP Moderated Poster Theater, Poster Hall, Hall C
Saturday, March 18, 2017, 1:00 p.m.-1:10 p.m.
Session Title: Stroke and AF: Thinking About the Heart
Abstract Category: 8. Arrhythmias and Clinical EP: Supraventricular/Ventricular Arrhythmias
Presentation Number: 1223M-07
- 2017 American College of Cardiology Foundation