Author + information
- Venkat Lakshmi Kishan Vuddandaa,b,
- Mohammad-Ali Jazayeria,b,
- Ling Lia,b,
- Mohit Turagama,b,
- Srikanth Yandrapallia,b,
- Madhav Lavua,b,
- Valay Parikha,b,
- Donita Atkinsa,b,
- Madhu Reddya,b,
- Dhanunjaya Lakkireddya,b and
- Shelby Kuttya,b
Background: Using indices of left atrial (LA) function (strain () and strain rate (SR) imaging) by two-dimensional speckle tracking echocardiography (2D-STE), it has been shown that LA appendage closure with the LARIAT procedure improves LA mechanics in intermediate term. We investigated the immediate effects of WATCHMAN device implantation (WDI) on phasic LA function indices.
Methods: In 25 patients who had transthoracic 2D-STE before and after WDI, indices of LA function (phasic volumes, strain and strain rate) were measured from apical four-chamber view with the reference point set at QRS. Comparisons were made between LA indices before and after WDI, using Wilcoxon Signed Rank test (IBM SPSS statistics version 22) and a p value (two tailed) less than 0.05 was considered statistically significant.
Results: Patients mean age was 76 ± 6.9 years, 60% were males, 56% had non-paroxysmal AF, and 36% had chronic heart failure. Assessment were done on echocardiograms performed at 1-730 days pre and 1-180 days post WDI. At a median follow up of 1 day significant improvements in the LA emptying fraction and both active and passive LA emptying were noted, however changes in deformation indices did not emerge significant (Table).
Conclusions: WDI resulted in improvement in LA function by volumetric indices, however no difference in strain and strain rate indices were found. Longer follow up may be necessary to ascertain the impact of ongoing atrial remodeling on LA mechanics, and how WDI differs from LARIAT in that regard.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Arrhythmias and Clinical EP: Devices 2
Abstract Category: 5. Arrhythmias and Clinical EP: Devices
Presentation Number: 1149-078
- 2017 American College of Cardiology Foundation