Author + information
- Pouria Alipour,
- Yaariv Khaykin,
- Zahra Azizi,
- Despina Michailidis,
- Amirhossein Sharifzad,
- Nikhil Nath,
- Evan Michaelov,
- Patrick Mallany,
- Sergio Conti,
- Alfredo Pantano and
- Atul Verma
Introduction: Radio Frequency catheter ablation has become the cornerstone for treatment of ventricular tachycardia (VT) in patients refractory to antiarrhythmic agents. Little is known about VT ablation performed outside clinical trial setting. This study aims to examine the success rate of Left and Right Outflow Tract VT (LVOT & RVOT respectively) ablation.
Methods: Baseline and follow-up data for 134 consecutive patients (mean age: 51.9±6.3 years, 41.7% Male, 17.9% LVOT, 66.4% RVOT, and 6.7% RVOT & LVOT) who underwent VT ablation (VTA) between 2005-2016, were retrospectively collected, and included in the analysis. ECG, and ambulatory monitoring data were collected at 1, 3, 6, and 12 months post ablation, any occurrence of VT was considered significant in the analysis. Patients were divided in 3 groups based on type of ablation, RVOT, LVOT, RVOT & LVOT. Rate of VT recurrence and VT-free survival was analyzed for all patients in the cohort.
Results: Overall 33.5% (28.4% RVOT, 37.9% LVOT, and 70% RVOT & LVOT) of patients manifested VT recurrence during follow-up post-procedure. Additionally, 1, 2, and 5 year VT-free survival rate was 69.3% (76.6% RVOT, 68.3% LVOT, and 48% RVOT & LVOT), 61.3% (70.9% RVOT, 49.6% LVOT, and 24% RVOT & LVOT), and 41.2% (61.2% RVOT, 24.8% LVOT, and 0% RVOT & LVOT) respectively (P=0.014).
Conclusions: Patients with RVOT VT treated with ablation have significantly better ablation outcomes compared to those with LVOT VT and those with substrate involving both outflow tracts.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Atrial Fibrillation and VT: Unique Populations and Solutions
Abstract Category: 8. Arrhythmias and Clinical EP: Supraventricular/Ventricular Arrhythmias
Presentation Number: 1151-095
- 2017 American College of Cardiology Foundation