Author + information
- Eric H. Shulman,
- Faraj Kargoli,
- Lynn Zaremski,
- Tina Shah,
- Luigi DiBiase,
- John Fisher,
- Kevin Ferrick and
- Andrew Krumerman
Background: No previous studies have examined the interaction between diabetes mellitus (DM) across a large Hispanic, Black and White cohort with the development of atrial fibrillation (AF).
Methods: We retrospectively followed 32,245 persons free of AF (46% Hispanic, 39% Black and 15% White, mean age 60 years) for subsequent incident AF. Incident AF was ascertained from electrocardiograms. DM was analyzed as a categorical variable (no DM as HbA1c < 5.7, pre-DM as HbA1c >= 5.7 to < 6.4 and DM as HbA1c >=6.4). Cox regression analysis controlled for baseline covariates: heart failure, gender, age, hypertension, systolic blood pressure, left ventricular hypertrophy and use of beta-blockers, calcium channel blockers or digoxin. Regression analysis was performed for the entire cohort and then stratified by race.
Results: Over a follow-up of 13 years, 3,395 AF cases occurred (mean age 70, 45% male). There was a significant difference between the incidence of DM by race (42% Hispanic, 41% Black and 33% White, see Table 1). However, in all regression cohorts, DM was not associated with development of AF (p-values > 0.20).
Conclusions: There is a clear difference in the incidence of DM by race. However, our study suggests that this difference is not an explanatory factor for the variable development of AF by race.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Arrhythmias and Clinical EP: AF Miscellaneous and Surgical Issues
Abstract Category: 6. Arrhythmias and Clinical EP: Other
Presentation Number: 1236-083
- 2017 American College of Cardiology Foundation