Author + information
- Juan Rico Mesaa,b,
- Rafael Correaa,b,
- Juan Fernando Agudeloa,b,
- Elsa Vasqueza,b,
- Alvaro Quinteroa,b,
- Gloria Saenza,b,
- Ricardo Fernandeza,b and
- Juan Ramireza,b
Background: Cardiac arrhythmias and electrocardiographic (ECG) abnormalities can occur in Orthotopic Heart Transplantation (OHT) Patients. There is no available data about the prevalence and outcomes of these alterations on outpatient Holter monitors.
Methods: An observational, descriptive study was performed. A database of 487 OHT patients between May 1985 and August 2016 was reviewed retrospectively and analyzed. All Holter monitors done on these patients were reviewed and the prevalence of various arrhythmias and Holter abnormalities were noted. Fisher's exact test was used to evaluate significant association between mortality, sex and Holter findings.
Results: Of the 487 OHT patients, only 46 had a Holter. Of those, 31 (65.9%) were male. Mean age at transplant was 37.7±17.8. The most common arrhythmia was sinus tachycardia (34.8%), followed by Atrial Flutter (4.3%) and Atrial Fibrillation (2.2%). The most common heart block was Right Bundle Branch Block (RBBB) (32.6%), followed by first-degree atrioventricular block (10.8%). Mortality and the presence of any Bundle Branch Block (BBB) had a statistical significant association (P 0.048). Although a trend was observed between mortality and the presence of RBBB itself, this did not reach statistical significance (p 0.058). There was not a significant association between Holter findings and sex (p 0.185).
Conclusions: Our study suggests a low prevalence of arrhythmias such as atrial flutter or atrial fibrillation, with high prevalence of RBBB and an association between mortality and the presence of any BBB. Further prospective studies are required to determine the need of Holter monitor follow up in OHT patients and the exact pathophysiological mechanism of our findings
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Arrhythmias and Clinical EP: Syncope and Other EP Issues
Abstract Category: 6. Arrhythmias and Clinical EP: Other
Presentation Number: 1279-091
- 2017 American College of Cardiology Foundation