Author + information
- Andreas P. Kalogeropoulosa,b,
- Panagiotis Savvoulidisa,b,
- Anita Sarafa,b,
- Fred Rodrigueza,b,
- Trenton Hoffmana,b,
- Cheryl Raskind-Hooda,b,
- Carol Hoguea,b and
- Wendy Booka,b
Background: Data on the prevalence and incidence of heart failure (HF) among adolescents and adults with repaired tetralogy of Fallot (rToF) are limited.
Methods: We identified 524 patients age 10 or older who received services for repaired tetralogy of Fallot (ICD9-CM code 745.2; repair was identified through codes V13.65 and V15.1) in our institution between 2008 and 2014 (cohort inception). Prevalent HF was defined as presence of ICD9-CM codes 428, 402.X1, 404.X1, and 404.X3 (Medicare definition) at cohort entry. Incident HF was defined as new HF-associated services after cohort entry.
Results: Median age was 32 years (Q1-Q3: 24-42); 55.3% were female; 69.5% were white, 19.7% black, and 10.9% of other or unknown race. Prevalence of HF at cohort entry was 203/524 (38.7%), with significantly higher rates after age 20 and exceeding 50% among those over age 40, Fig. 1. Among the 321 patients without HF at entry, 163 received HF-related services over a median of 3.0 (0.8-5.5) years. By 5 years, 50.2% of patients received new HF-related services. Risk for HF was higher among those of age 40 or older (Fig. 2) and did not differ in female vs. male patients (hazard ratio [HR] 1.02; 95%CI: 0.74-1.40; P=0.90). However, blacks had significantly higher risk for HF vs. whites (HR: 1.68; 95%CI: 1.18-2.38; P=0.004) in age- an sex-adjusted models.
Conclusions: In a contemporary rToF population of adolescents and adults, HF prevalence increased sharply with age and 5-year incidence was 50% with higher rates among blacks and those over age 40.
Moderated Poster Contributions
Congenital Heart Disease and Pulmonary Hypertension Moderated Poster Theater, Poster Hall, Hall C
Friday, March 17, 2017, 10:45 a.m.-10:55 a.m.
Session Title: Congenital Heart Disease: To the Third Decade and Beyond
Abstract Category: 9. Congenital Heart Disease: Adult
Presentation Number: 1131M-09
- 2017 American College of Cardiology Foundation