Author + information
- Talha Niaz,
- Joseph Poterucha,
- Jonathan Johnson,
- Timothy Olson and
- Donald Hagler
Background: Bicuspid aortopathy has been a center point of interest in patients with bicuspid aortic valve (BAV). Our aim was to study the age wise growth of aorta in patients with isolated BAV from infancy to young adult age.
Methods: The Mayo Clinic echocardiography database was retrospectively analyzed to identify pediatric and young adult patients (≤ 22 years) diagnosed with BAV from 1990-2015. All echocardiograms performed prior to any intervention on aortic valve or aorta were analyzed for aortic measurements formatted as z-scores.
Results: We identified a total of 1010 patients with BAV, out of which 619 had isolated BAV. The distribution of morphology of cusp fusion in isolated BAV was right-left fusion (RL) in 419 (67.7%), right-non coronary fusion (RN) in 197 (31.8%) and left-non coronary fusion (LN) in 3 (0.5%) subjects. Mid-ascending aorta was abnormally dilated (defined as z-score > 2) during pediatric and young adult age, and it was present even during the first year of life in patients with RN fusion. Moreover patients with RN fusion had significantly larger mid-ascending aorta diameter than patients with RL fusion (p<0.001). There was no significant sinus of Valsalva dilation, though patients with RL fusion had larger sinus of Valsalva diameter as compared to RN fusion (p<0.04). There was a period of peak growth of aorta around 8 years of age.
Conclusions: Abnormal dilation of ascending aorta begins in childhood and shows interesting growth patterns from infancy to adolescence into adulthood.
Moderated Poster Contributions
Congenital Heart Disease and Pulmonary Hypertension Moderated Poster Theater, Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-3:55 p.m.
Session Title: Predicting Outcomes in Pediatric Heart Disase
Abstract Category: 10. Congenital Heart Disease: Pediatric
Presentation Number: 1171M-03
- 2017 American College of Cardiology Foundation