Author + information
- Ghanshyam Palamaner Subash Shantha,
- Anita Kumar,
- Kongkiat Chaikriangkrai,
- Chakradhari Inampudi,
- Gardar Sigurdsson and
- Michael Giudici
Background: There is scant data with regards to the gender differences in the rates of hospitalizations for decompensated heart failure (DHF) among adult patients with congenital heart diseases (CHD) in the United States. In this retrospective cohort study we assessed gender differences in hospitalization rates for DHF among adult patients with CHD in the United States and further assessed the temporal trends in the last 15 years.
Methods: National Inpatient Sample (NIS), a publically available dataset, reports data on 8 million hospitalizations from about 1000 hospitals from 46 states. From this, we abstracted data on 192,444 consecutive patients with CHD hospitalized from 1998 – 2012 (study cohort). From this study cohort, we further abstracted data on the rates of hospitalizations for DHF and assessed gender differences in hospitalization rates over 3 periods: 1998 – 2002, 2003 – 2007 and 2008 – 2012.
Results: Of the 192,444 study cohort participants, 101,367 (53%) were women (W) and 91,077 (47%) were men (M). Men were significantly older compared to women (M: 47 years, W: 44 years, P = 0.033). Hospitalization rates for DHF were significantly higher in women than men (W: 76% vs M: 62%) (P < 0.001) in the total cohort. Temporal trends over the 15 year period (1998 – 2012) consistently showed higher hospitalization rates for DHF in women compared to men [(1998 – 2002: W – 71%, M – 66%), (2003 – 2007: W – 77%, M – 61%), (2008 – 2012: W – 78%, M – 62%)]. Multi-variate logistic regression analysis [(adjusted for age, diabetes diagnosis (DM), hypertension diagnosis (HTN), previous stroke] showed significantly increased odds of hospitalizations (Odds Ratios ranging from 1.22-1.27) for DHF in women compared to men in the CHD cohort over all the 3 time periods.
Conclusions: Our analysis suggests that women with CHD have consistently had an increased probability of hospitalization for DHF compared to men for the last 15 years in the United States. Our findings are in contrary to the available literature that supports a better prognosis among women with heart failure compared to their male counterparts among heart failure patients without CHD. The reason behind this discrepancy is not known and deserves further investigation.
Moderated Poster Contributions
Congenital Heart Disease and Pulmonary Hypertension Moderated Poster Theater, Poster Hall, Hall C
Sunday, March 19, 2017, 10:00 a.m.-10:10 a.m.
Session Title: Things That Matter in Adult Congenital Heart Disease
Abstract Category: 9. Congenital Heart Disease: Adult
Presentation Number: 1302M-05
- 2017 American College of Cardiology Foundation