Author + information
- Ololade Akintoyea,b,
- Curtis Traversa,b,
- William Bordera,b,
- Christopher J. Petita,b,
- Erik Michelfeldera,b and
- Ritu Sachdevaa,b
Background: The role of tricuspid annular plane systolic excursion (TAPSE) in evaluating right ventricular (RV) function in hypoplastic left heart syndrome (HLHS) has not been fully explored. We sought to evaluate the relation between TAPSE and RV fractional area change (FAC) and cardiac index (CI) during the inter-stage period.
Methods: TAPSE and FAC measured within7 days of pre-Glenn catheterization from Dec 2008 to Mar 2016 were analyzed. TAPSE z-score was calculated using published normal values for structurally normal hearts. Normal RV systolic function was defined as FAC ≥ 40%. TAPSE was correlated with FAC and CI derived by Fick.
Results: Among 86 subjects, patient characteristics, TAPSE, and TAPSE aged- based z-score were similar between those with normal (N = 55) and reduced (N = 31) RV function (Table). There was no significant correlation between FAC and TAPSE or TAPSE z-score (r=0.13, 0.08, respectively). The TAPSE z-score in those with normal FAC was lower than structurally normal hearts (μ = −3.97, p < 0.001). In those with simultaneous cardiac catheterization (N = 36), there was no significant correlation between either TAPSE and CI (r=0.26, p = 0.121) or RVFAC and CI (r = 0.30, p = 0.073).
Conclusions: In HLHS, TAPSE was significantly lower than normal values even in those with normal FAC. Lack of correlation with FAC suggests that TAPSE does not fully describe global RV function. Neither TAPSE nor FAC correlated with CI, and are likely too simplistic to describe ventricular-vascular interactions.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Congenital Heart Disease: Innovations in Single Ventricle Heart Disease
Abstract Category: 10. Congenital Heart Disease: Pediatric
Presentation Number: 1182-015
- 2017 American College of Cardiology Foundation